HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 19784341, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | HCID 19784372 | HCID 19784372 | — |
| Product | HCID 19784341 | HCID 19784341 | 50.2% |
Reaction Steps
2.6 g (7.9 mmol) of the amine from Example 25 were reduced with 2.8 g (23.7 mmol) of triethylsilane and 9.0 g of trifluoroacetic acid in a similar manner to Example 14. 1.7 g of 4-(N-(4-fluorobenzyl)-N-methylamino)-1-(4-tolyl)piperidine fumarate were obtained. Melting point 146° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05260318 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-a5df3e4c1f104d8d978d32c0f60efed6 |
| Source note | uspto-grants-1993_11 |