HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 19784351, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 19784347 | HCID 19784347 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 19784351 | HCID 19784351 | 75.1% |
Reaction Steps
2.5 g (7 mmol) of the product from Example 27 in 140 ml of 1M sodium hydroxide solution/ethanol (1:1) were refluxed for 5 hours. The mixture was then worked up in a similar manner to Example 16. 1.8 g of 1-(4-carboxyphenyl)-4-(N-(4-fluorobenzyl)-N-methylamino)piperidine were obtained. Melting point: 256°-258° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05260318 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-497a9a659fbc44f1b2f615939b100695 |
| Source note | uspto-grants-1993_11 |