HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Methyl (2-chloromethyl-5-methylphenoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Methyl (2-hydroxymethyl-5-methylphenoxy)acetate | HCID 54364037 | — |
| Catalyst | Pyridine | HCID 1049 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl (2-chloromethyl-5-methylphenoxy)acetate | HCID 53932989 | 55.4% |
Reaction Steps
By the method of Example 1, Step J, 9.21 g (0.044 mole) of methyl (2-hydroxymethyl-5-methylphenoxy)acetate was reacted with 7.40 g (0.062 mole) of thionyl chloride and 5 drops of pyridine in 50 mL of methylene chloride, yielding 5.57 g of methyl (2-chloromethyl-5-methylphenoxy)acetate as an orange liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05262390 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-557da11b291d4f04a4f296f1d472bf4a |
| Source note | uspto-grants-1993_11 |