HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N-methyl-5-nitropyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-methyl-5-nitropyridin-2-amine | HCID 265883 | — |
Reaction Steps
3-Nitro-6-chloropyridine (5 g, 31.5 mmol) was added to 10 ml of a 30% solution of methylamine in ethanol, followed by reaction at room temperature for 5 minutes. Then, recrystallization from chloroform-hexane gave 4.92 g of the intended product as yellow crude crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05262415 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-44b7ea052e4c4c96a317178936f110bd |
| Source note | uspto-grants-1993_11 |