4-Ethylpyridine → 1-(3,4-Dichlorophenyl)-3-(4-pyridyl)butane

HRID 257466Notes

Reaction equation

HRID 257466 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2].[Cl:9][C:10]1[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=1[Cl:19])[CH2:13][CH2:14]Br>>[Cl:9][C:10]1[CH:11]=[C:12]([CH2:13][CH2:14][CH:1]([C:3]2[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=2)[CH3:2])[CH:16]=[CH:17][C:18]=1[Cl:19]

Participants

3

Reactant 2

HCID 108224-EthylpyridineHCID 151493894-(2-Bromoethyl)-1,2-dichlorobenzene

Product 1

HCID 197833141-(3,4-Dichlorophenyl)-3-(4-pyridyl)butaneYield 44.7%

Procedure

1.0 g (9.35 mmol) of 4-ethylpyridine and 2.37 g (9.35 mmol) of 3,4-dichlorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 1.17 g of the desired compound (yield: 44.6%).

Workup

  1. customThe reaction product was purified

Sources & evidence

ORD record
ord-be6104b6208b4ecb9c31f03db979c332
Source dataset
uspto-grants-1993_11
Patent number
US05262420

Reaction notes

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