3-Ethyl-4-methylpyridine → 1-(3-Chlorophenyl)-3-(3-ethyl-4-pyridyl)-propane

HRID 257472Notes

Reaction equation

HRID 257472 reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9])[CH3:2].[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=1)[CH2:14][CH2:15]Br>>[Cl:10][C:11]1[CH:12]=[C:13]([CH2:14][CH2:15][CH2:9][C:8]2[CH:7]=[CH:6][N:5]=[CH:4][C:3]=2[CH2:1][CH3:2])[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 682543-Ethyl-4-methylpyridineHCID 1401401-(2-Bromoethyl)-3-chlorobenzene

Product 1

HCID 197833501-(3-Chlorophenyl)-3-(3-ethyl-4-pyridyl)-propaneYield 50.7%

Procedure

1.13 g (9.35 mmol) of 3-ethyl-4-methylpyridine and 2.05 g (9.35 mmol) of m-chlorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 1.23 g of the desired compound (yield: 50.7%).

Workup

  1. customThe reaction product was purified

Sources & evidence

ORD record
ord-e82411eb88074f858b4cae795b5ce223
Source dataset
uspto-grants-1993_11
Patent number
US05262420

Reaction notes

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