HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethyl-4-methylpyridine → 1-(3-Trifluoromethylphenyl)-4-(3-ethyl-4-pyridyl)-butane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethyl-4-methylpyridine | HCID 68254 | — |
| Reactant | 1-(3-Bromopropyl)-3-(trifluoromethyl)benzene | HCID 19783367 | — |
| Product | 1-(3-Trifluoromethylphenyl)-4-(3-ethyl-4-pyridyl)-butane | HCID 14883795 | 80.5% |
Reaction Steps
1.83 g (15.1 mmol) of 3-ethyl-4-methylpyridine and 4.03 g (15.1 mmol) of 1-bromo-3-(3-trifluoromethylphenyl) propane were reacted in the same manner as in Example 26. The reaction compound was purified to obtain 3.73 g of the desired compound (yield: 80.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05262420 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-3b9d8da1be95426a9dea1dec64ae6189 |
| Source note | uspto-grants-1993_11 |