HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine, 4-ethyl-3-methyl- → 1-(3-Trifluoromethylphenyl)-4-(3-methyl-4-pyridyl)-pentane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine, 4-ethyl-3-methyl- | HCID 34088 | — |
| Reactant | 1-(3-Bromopropyl)-3-(trifluoromethyl)benzene | HCID 19783367 | — |
| Product | 1-(3-Trifluoromethylphenyl)-4-(3-methyl-4-pyridyl)-pentane | HCID 14883796 | 47.5% |
Reaction Steps
1.83 g (15.1 mmol) of 3-methyl-4-ethylpyridine and 4.03 g (15.1 mmol) of 1-bromo-3-(3-trifluoromethylphenyl)-propane were reacted in the same manner as in Example 26. The reaction product was purified to obtain 2.20 g of the desired compound (yield: 47.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05262420 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-79da715842cc4ed5a0a75cfeaac6dd4a |
| Source note | uspto-grants-1993_11 |