Trifluoroacetic acid → HCID 10421193, compound

Participants

Reaction Steps

Treat the product of Step 1 (2.79 g) in CH2Cl2 (40 ml) with trifluoroacetic acid (10 ml) at room temperature for 18 hr. Concentrate the reaction mixture in vacuo. Dissolve the residue in CH2Cl2 and concentrate in vacuo (twice). Dissolve the white solid in EtOAc and extract with 10% sodium bicarbonate solution. Dry (MgSO4) the EtOAc and concentrate in vacuo to give the title compound, a white solid (1.53 g) m.p. 94°-95°, [α]D26 =-1.3° (MeOH).

Provenance & Evidence