HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 14390730, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 14390733 | HCID 14390733 | — |
| Reactant | Dichloromethane methanol ammonium hydroxide | HCID 21896990 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 14390730 | HCID 14390730 | — |
Reaction Steps
Treat the product from Step 1 with methanol saturated with ammonia as described in Example 12, Step 3 (before chromatography). Treat the resultant residue with zinc powder as described in Example 17. Chromatograph the product on flash grade silica gel using CH2Cl2 :MeOH:NH4OH (97.5:2.5:0.25) to give the title compound, [α]D26 =-118.2° (MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05262436 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-4996b6c9242c4904896ef3b122bae883 |
| Source note | uspto-grants-1993_11 |