HCID 53792258, compound → HCID 19783203, compound

HRID 257589Notes

Reaction equation

HRID 257589 reaction equation
C([NH:5][S:6]([C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH3:17])=[CH:11][C:10]=1[C:18]1[CH:23]=[CH:22][C:21]([CH2:24][CH:25]([C:32](=O)[CH2:33][CH2:34][CH2:35][CH3:36])[C:26](=NOC)[C:27]#[N:28])=[C:20]([F:38])[CH:19]=1)(=[O:8])=[O:7])(C)(C)C.Cl.[Cl:40][C:41]1[CH:46]=[CH:45][C:44]([N+:47]([O-:49])=[O:48])=[CH:43][C:42]=1[NH:50][NH2:51]>>[CH2:33]([C:32]1[C:25]([CH2:24][C:21]2[CH:22]=[CH:23][C:18]([C:10]3[CH:11]=[C:12]([CH2:15][CH2:16][CH3:17])[CH:13]=[CH:14][C:9]=3[S:6](=[O:8])(=[O:7])[NH2:5])=[CH:19][C:20]=2[F:38])=[C:26]([C:27]#[N:28])[N:50]([C:42]2[CH:43]=[C:44]([N+:47]([O-:49])=[O:48])[CH:45]=[CH:46][C:41]=2[Cl:40])[N:51]=1)[CH2:34][CH2:35][CH3:36]

Participants

3

Reactant 2

HCID 53792258HCID 53792258, compoundHCID 67885116HCID 67885116, compound

Product 1

HCID 19783203HCID 19783203, compound

Procedure

The reaction of 3-[[2'-(N-t-butylsulfamoyl)-3-fluoro-5'-n-propylbiphenyl-4-yl]methyl]-2-methoxyimino-4-oxooctanenitrile (from Step C) with 2-chloro-5-nitrophenylhydrazine hydrochloride according to the procedure of Example 1, Step G, yields the title compound.

Sources & evidence

ORD record
ord-b8f18e9fa52345ae837177b8154152cf
Source dataset
uspto-grants-1993_11
Patent number
US05262412

Reaction notes

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