Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 257590Generated: October 28, 2026

2-Fluorobenzoic acid → HCID 19783227, compound

https://huagongshe.com/reaction/257590

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluorobenzoic acidHCID 9935—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
ReactantImidazolateHCID 3386966—
ReactantHCID 19783203HCID 19783203—
ProductHCID 19783227HCID 19783227—

Reaction Steps

By the method of Example 1, Step H, 2-fluorobenzoic acid is converted to its imidazolide and reacted with 3-n-butyl-1-(2-chloro-5-nitrophenyl)-4-[(3-fluoro-5'-n-propyl-2'-sulfamoylbiphenyl-4-yl)methyl]-1H-pyrazole-5-carbonitrile (from Step D) in the presence of DBU to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05262412
Source datasetuspto-grants-1993_11
ORD IDord-c2d829f9de6e4b1cae986cb0e71728a9
Source noteuspto-grants-1993_11