Ethyl Acetate → HCID 10320206, compound

Participants

Reaction Steps

A solution of ethyl 3-[2-(4,5-diphenyl-2oxazolyl)-ethyl]phenyl-2-propenoate (1.02 g, 2.4 mmol) in ethyl acetate (50 mL) was hydrogenated over 10% palladium on charcoal (0.06 g) at 35 psi. After 27 hours, the mixture was filtered, concentrated and the residue subjected to chromatography on a column of silica gel using a mixture of ethyl acetate and hexanes (9:1) as eluent. Elution gave ethyl 3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]benzene propanoate (0.92 g, 90%) as an oil.

Provenance & Evidence