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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25765Generated: October 29, 2026

Potassium Carbonate → [6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine

https://huagongshe.com/reaction/25765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 22566498HCID 22566498—
Reactant4-(Bromomethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolineHCID 22566535—
ReactantHCID 22566543HCID 22566543—
Product[6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamineHCID 10406857—

Reaction Steps

4-(4-tert-Butylphenylsulfanylmethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline 60 mg of 4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline, 46 mg of potassium carbonate, and 25 μL of 4-tert-butylphenylthiophenol reacted to give 9 mg of the title compound as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858627B2
Source datasetuspto-grants-2005_02
ORD IDord-0e373836112749a6946d93ae9d53c357
Source noteuspto-grants-2005_02