HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → [6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Thioacetic acid S-[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl] ester | HCID 9998207 | — |
| Reactant | 4-(Bromomethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline | HCID 22566535 | — |
| Reactant | HCID 178418634 | HCID 178418634 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | [6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine | HCID 10406857 | — |
Reaction Steps
Thioacetic acid S-[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl] ester 776 mg of 4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline in 16 mL of methylene chloride was treated with 155 μL of thioacetic acid and 303 μL of triethylamine to give 100 mg of the title compound as a foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858627B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-9ed43edf77e04ccc9d4905866af16f7a |
| Source note | uspto-grants-2005_02 |