Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Ethyl 5-(1-acetyl-1H-indol-3-yl)pent-2-enoate | HCID 53953280 | — |
| Product | HCID 19781434 | HCID 19781434 | 79.9% |
Reaction Steps
A mixture of olefin 32 (5.0 g, 17.5 mmol) and benzylamine (7.7 mL, 70 mmol) was heated at 80° C. for 20 hours. The cooled reaction mixture was applied directly to a flash chromatography column (silica, 30% ethyl acetate/hexanes) to give the Micheal adduct 33 (4.9 g) as a viscous yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05264420 |
|---|
| Source dataset | uspto-grants-1993_11 |
|---|
| ORD ID | ord-ed2f5ef2241f4f2b9cb1f01ad77386a7 |
|---|
| Source note | uspto-grants-1993_11 |
|---|
