HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobutyryl chloride → 5-(4-Diethylamino-butyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobutyryl chloride | HCID 70225 | — |
| Reactant | 5,10-Dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-one | HCID 201327 | — |
| Reactant | 5-(4-bromobutyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one | HCID 10737151 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 5-(4-Diethylamino-butyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one | HCID 15115499 | — |
Reaction Steps
The 5-(4-bromobutyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one, starting material, was synthesized similarly to the starting material described in Example 1, from 5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one and 4-bromobutyryl chloride. The yield is 74.3% of the theoretical yield and the melting point is 159°-161° C. (toluene).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05264432 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-d7b8681b86894f4c8a6680f86fef89c1 |
| Source note | uspto-grants-1993_11 |