Methyl iodide → 131988-12-0

HRID 257865Notes

Reaction equation

HRID 257865 reaction equation
[CH3:1][I:2].[CH2:3]([O:5][C:6]1[C:7]([C:11]2[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=2)=[N:8][S:9][N:10]=1)[CH3:4]>CC(C)=O>[I-:2].[CH2:3]([O:5][C:6]1[C:7]([C:11]2[CH:12]=[N+:13]([CH3:1])[CH:14]=[CH:15][CH:16]=2)=[N:8][S:9][N:10]=1)[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 15180131Pyridine, 3-(4-ethoxy-1,2,5-thiadiazol-3-yl)- (9CI)

Product 1

HCID 15819042131988-12-0

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(4-ethoxy-1,2,5-thiadiazol-3-yl)pyridine (520 mg, 2.5 mmol) in acetone (10 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.72 g (83%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.72 g (83%)

Sources & evidence

ORD record
ord-1a202914b9684dd79d29ff1b6a288533
Source dataset
uspto-grants-1993_11
Patent number
US05264444

Reaction notes

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