Methyl iodide → HCID 19075352, compound

HRID 257881Notes

Reaction equation

HRID 257881 reaction equation
[CH3:1][I:2].[CH2:3]([O:7][C:8]1[C:9]([C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)=[N:10][S:11][N:12]=1)[C:4]#[C:5][CH3:6]>CC(C)=O>[I-:2].[CH2:3]([O:7][C:8]1[C:9]([C:13]2[CH:14]=[N+:15]([CH3:1])[CH:16]=[CH:17][CH:18]=2)=[N:10][S:11][N:12]=1)[C:4]#[C:5][CH3:6]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19075318HCID 19075318, compound

Product 1

HCID 19075352HCID 19075352, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 7.5 mmol) and 3-(4-(2-butynyloxy)-1,2,5-thiadiazol-3-yl)pyridine (578 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.88 g (95%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.88 g (95%)

Sources & evidence

ORD record
ord-5aa6ccdbb4b94cfbb5f5e579b10e7908
Source dataset
uspto-grants-1993_11
Patent number
US05264444

Reaction notes

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