HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-(2-Methylphenyl)-2-oxo-2,6,7,8-tetrahydrocyclopenta[g][1]benzopyran-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 10450416 | HCID 10450416 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(2-Methylphenyl)-2-oxo-2,6,7,8-tetrahydrocyclopenta[g][1]benzopyran-3-carboxylic acid | HCID 10358630 | — |
Reaction Steps
A mixture of ethyl 4-(2-methylphenyl)-2-oxo-2,6,7,8-tetrahydrocyclopenta[g][1]benzopyran-3-carboxylate (5.0 g), concentrated hydrochloric acid (13 ml) and acetic acid (25 ml) was refluxed for 12 hours. To this reaction mixture was added water, whereupon 4-(2-methylphenyl)-2-oxo-2,6,7,8-tetrahydrocyclopenta[g][1]benzopyran-3-carboxylic acid was obtained as crystals (4.5 g, 97.8%). Recrystallization from acetone-hexane gave colorless prisms, mp 213°-214° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05264454 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-25b501845b9d4c5cbd894ff881b46bbe |
| Source note | uspto-grants-1993_11 |