HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylethanethiol → 6-(3-Methoxyphenyl)-2,2-dimethyl-4-phenethylsulfanylmethyl-1,2-dihydroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylethanethiol | HCID 78126 | — |
| Reactant | (3-Methoxyphenyl)boronic acid | HCID 2734370 | — |
| Reactant | Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester | HCID 20760320 | — |
| Product | 6-(3-Methoxyphenyl)-2,2-dimethyl-4-phenethylsulfanylmethyl-1,2-dihydroquinoline | HCID 10341807 | — |
Reaction Steps
Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester was coupled with 3-methoxyphenylboronic acid. Bromination and coupling reaction with 2-phenylethanethiol gave 21 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858627B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-7c56a04383ed4063bf8cdbd4df45e8e4 |
| Source note | uspto-grants-2005_02 |