Formamide → HCID 86747391, compound

HRID 258062Notes

Reaction equation

HRID 258062 reaction equation
S(=[C:3]1[CH:11]=[C:7]([C:8]([Cl:10])=[O:9])[C:6](N)=[C:5]([C:13]([Cl:15])=[O:14])[CH2:4]1)=O.C([NH2:18])=O>CCOCC>[ClH:10].[NH2:18][C:3]1[CH:11]=[C:7]([C:8]([Cl:10])=[O:9])[CH:6]=[C:5]([CH:4]=1)[C:13]([Cl:15])=[O:14]

Participants

4

Reactant 2

HCID 713FormamideHCID 86747392HCID 86747392, compound

Product 1

HCID 86747391HCID 86747391, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

5.0 g of 5-sulfinyl amino isophthaloyl chloride (Example 1) was dissolved in 150 ml of ether, and anhydrous hydrogen chloride gas was bubbled through for 2 hours. Beige colored precipitate, which weighed 3.71 g after filtration, was obtained. This product was soluble in an amide solvent, such as N,N'-dimethyl acetamide or formamide. However, solution NMR of this product could not be obtained, since it polymerizes in those solvents. Elemental analysis calculated as C8H6NO2Cl3 : Theory: C:37.76, H:2.38 N:5.50. Found C:40.98 H:2.74, N:6.33.

Workup

  1. customanhydrous hydrogen chloride gas was bubbled through for 2 hours
  2. filtrationafter filtration
  3. customwas obtained
  4. customHowever, solution NMR of this product could not be obtained, since it
  5. custompolymerizes in those solvents

Sources & evidence

ORD record
ord-017a44c420e6488fa0dbe5bc69f873d0
Source dataset
uspto-grants-1993_11
Patent number
US05264543

Reaction notes

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