HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 1H-indole-2-carbonyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Indole-2-carboxylic acid | HCID 72899 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1H-indole-2-carbonyl Chloride | HCID 11816208 | — |
Reaction Steps
A mixture of indole-2-carboxylic acid (2.18 g), N,N-dimethylformamide (52 mg) and thionyl chloride (1.0 ml) in dry dichloromethane (22 ml) was refluxed for 1 hour to give a solution of 2-indolylcarbonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05264433 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-47d4ab4a1d1343a3b30f1c071df0524a |
| Source note | uspto-grants-1993_11 |