Sulfuric Acid → HCID 136403420, compound

Participants

Reaction Steps

22.0 g of methyl orthoformate was dropped in about 2 hours in a mixture of 10 g of 2-nitroiminoimidazolidine, 20 ml of 1,3-dimethyl-2-imidazolidinone and 0.05 g of sulfuric acid at 150° C., followed by heating under reflux for further 1 hour while removing the resultant distillate by means of the Dean-Stark trap. After cooling to room temperature, the mixture was poured into water, and extracted with ethyl acetate. After washing with water, the extract was dried with anhydrous magnesium sulfate, after which the solvent was distilled off under reduced pressure. The resultant crude crystals were sludged with ether to give 1.9 g of 1-dimethoxymethyl-2-nitroiminoimidazolidine.

Provenance & Evidence