Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2',4'-Trichloroacetophenone → 2-Chloro-1-(2,5-dichlorophenyl)ethan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2',4'-Trichloroacetophenone | HCID 20250 | — |
| 반응물 | 2,4-Dichloro-alpha-(chloromethyl)benzenemethanol | HCID 94351 | — |
| 반응물 | 2-Chloro-1-(3,4-dichlorophenyl)ethan-1-one | HCID 316188 | — |
| 반응물 | 2-Chloro-1-(2,5-dichlorophenyl)ethanone | HCID 2113292 | — |
| 반응물 | 2-Chloro-1-(3,4-dichloro-phenyl)-ethanol | HCID 12291292 | — |
| 생성물 | 2-Chloro-1-(2,5-dichlorophenyl)ethan-1-ol | HCID 12291293 | — |
반응 단계
Cultivation, reaction and purification were carried out in the same way as described in Example 9 except that 2-chloro-1-(2', 4'-dichlorophenyl) ethanon, 2-chloro-1-(3', 4'-dichlorophenyl) ethanone, 2-chloro-1-(2', 5'-dichlorophenyl) ethanone were used as substrate, and (-)-2-chloro-1-(2', 4'-dichlorophenyl) ethanol, (-)-2-chloro-1-(3', 4'-dichlorophenyl) ethanol, (-)-2-chloro-1-(2', 5'-dichlorophenyl) ethanol was obtained. The yield, specific rotation and optical purity determined by high-performance liquid chromatography were shown in Table 6.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05266485 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-6e0b950ca30e49deaa136a75d3dd2b19 |
| 출처 메모 | uspto-grants-1993_11 |