Hydrochloric Acid → HCID 67753607, compound

Participants

Reaction Conditions

Reaction Steps

To a cold (ice bath) stirred solution of Example 3 (145 mg, 0.34 mmol) in ether (5 mL) was added ethereal hydrochloride (2 mL). After stirring at 0° C. for 0.5 h, the resulting suspension was filtered to give the title compound as a white solid (135 mg, 86%), mp 221.0°-3.0° C.; MS(CI): 425 (M+H); NMR (300 MHz, DMSO-d6): 1.14(t, 3H, J=6.3 Hz), 1.19(m, 4H), 2.50(s, submerged by DMSO, 2H), 2.75(m, 2H), 3.40-3.55(br m, 4H), 3.83(s, 2H), 3.91(br s, 1H), 4.20-4.40(br m, 2H), 4.48(s, 1H), 7.01(m, 3H), 7.33(m, 4H), 7.93(d, 1H, J=8.0 Hz), 10.08(br s, 1H).

Provenance & Evidence