Ethyl cyanoacetate → HCID 131718258, compound

Participants

Reaction Steps

In a similar apparatus as described in example 2, 7.7 mmoles of tetra-n-butyl ammonium hydroxide (20% solution in toluene/methanol) in 40 ml of dry toluene and heated to +75° C. to +85° C. Ethylcyanoacetate (9.4 mmoles) was slowly added. Simultaneously an azeotrope of toluene-water was distilled out slowly over a period of 3 hours. After all toluene had distilled over, the flask was cooled to room temperature slowly. A solid product separated out, which was repeatedly washed with dry hexane. The initiator (tetra-n-butyl ammonium ethylcyanoacetate) thus formed was dried in vacuum and stored at room temperature under nitrogen or argon.

Provenance & Evidence