Boron trifluoride etherate → HCID 19737804, compound

Participants

Reaction Steps

2.44 g (11.3 mmol) of 3,5-dimethyl-2-(2-methyl-2-propen-1-yl)-6-(2-propen-1-yl)phenol (Compound No. 1) was dissolved in 20 ml of 1,2-dichloroethane, and 0.42 ml (3.39 mmol) of boron trifluoride etherate was added thereto at 0° C. The above mixture was then stirred in an atmosphere of argon gas for 4 hours, poured into an aqueous solution of sodium hydrogencarbonate, and extracted with ethyl acetate. The thus obtained extract layer was washed successively with water and a saturated aqueous solution of sodium chloride, dried over magnesium sulfate, and then concentrated, whereby 2.37 g of a crude 2,3-dihydro-2,2,4,6-tetramethyl-7-(2-propen-1-yl)benzo[b]furan (Compound No. 2) was obtained as a yellow oily material.

Provenance & Evidence