HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-acetoxynonane → 7-[N-(4(R)-hydroxy-2-nonynyl)methanesulfonamido]heptanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-acetoxynonane | HCID 13104716 | — |
| Reactant | ethyl 7-[N-(4-acetoxy-8,8-dimethylnonyl)methanesulfonamido]heptanoate | HCID 20327702 | — |
| Reactant | 1-Chloro-4-acetoxy-8,8-dimethylnonane | HCID 20386036 | — |
| Product | 7-[N-(4(R)-hydroxy-2-nonynyl)methanesulfonamido]heptanoic acid | HCID 22798404 | — |
Reaction Steps
The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-chloro-4-acetoxy-8,8-dimethylnonane (Example D). The product of Step A is thus ethyl 7-[N-(4-acetoxy-8,8-dimethylnonyl)methanesulfonamido]heptanoate. The subsequent step yields 7-[N-(4-hydroxy-8,8-dimethylnonyl)methanesulfonamido]heptanoic acid (B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04033996 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-8d06b9b93cb34b699b77c4e79b54594c |
| Source note | uspto-grants-1977_07 |