1-Chloro-4-acetoxynonane → 7-[N-(4-Hydroxy-(E)-2-nonenyl)methanesulfonamido]heptanoic Acid

HRID 258616Notes

Reaction equation

HRID 258616 reaction equation
ClCCCC(OC(=O)C)CCCCC.BrCC=CC(OC(=O)C)CCCCC.C([CH:31]([CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][N:40]([CH2:45]/[CH:46]=[CH:47]/[CH:48]([O:54]C(=O)C)[CH2:49][CH2:50][CH2:51][CH2:52][CH3:53])[S:41]([CH3:44])(=[O:43])=[O:42])[C:32]([OH:34])=[O:33])C>>[OH:54][CH:48]([CH2:49][CH2:50][CH2:51][CH2:52][CH3:53])/[CH:47]=[CH:46]/[CH2:45][N:40]([CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:31][C:32]([OH:34])=[O:33])[S:41]([CH3:44])(=[O:42])=[O:43]

Participants

4

Reactant 3

HCID 131047161-Chloro-4-acetoxynonaneHCID 20327696ethyl 7-[N-(4-acetoxy-(E)-2-nonenyl)methanesulfonamido]heptanoic acidHCID 540485691-Bromo-4-acetoxy-2-nonene

Product 1

HCID 203276727-[N-(4-Hydroxy-(E)-2-nonenyl)methanesulfonamido]heptanoic Acid

Procedure

The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-bromo-4-acetoxy-2 -nonene (Example H). The product of Step A is thus ethyl 7-[N-(4-acetoxy-(E)-2-nonenyl)methanesulfonamido]heptanoic acid (B).

Workup

  1. customThe synthesis of this compound

Sources & evidence

ORD record
ord-11ca4b68e33b4197adc1837835462779
Source dataset
uspto-grants-1977_07
Patent number
US04033996

Reaction notes

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