N,N-Dimethylethylenediamine → HCID 178483749, compound

Participants

Reaction Steps

4-Chloro-N(1H-tetrazol- 5-yl)quinaldamide (0.3 g), N,N-dimethylethylenediamine (6 ml) and water (2 ml) were heated at 100° for 8 hours. The excess of N,N-dimethylethylenediamine was distilled off under reduced pressure and the residue was treated with aqueous hydrochloric acid to pH 1. The solid, in water (5 ml), was treated with 2 N sodium hydroxide to give a solution pH 4. The solid which crystallised from this solution was collected and dried, m.p. 200° (d).

Provenance & Evidence