Sodium borohydride → 4-Benzenesulphonamido-1-(4-phenyl-4hydroxybutyl)piperidine

HRID 258720Notes

Reaction equation

HRID 258720 reaction equation
[C:1]1([S:7]([NH:10][CH:11]2[CH2:16][CH2:15][N:14]([CH2:17][CH2:18][CH2:19][C:20]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[O:21])[CH2:13][CH2:12]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[BH4-].[Na+]>>[C:1]1([S:7]([NH:10][CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][CH2:19][CH:20]([C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)[OH:21])[CH2:15][CH2:16]2)(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 536955074-Benzenesulphonamido-1-(4-phenyl-4-oxobutyl)piperidine

Product 1

HCID 214265224-Benzenesulphonamido-1-(4-phenyl-4hydroxybutyl)piperidine

Procedure

4-Benzenesulphonamido-1-(4-phenyl-4-oxobutyl)piperidine prepared according to Example 2 may be reduced using sodium borohydride to give the title compound.

Sources & evidence

ORD record
ord-4f609690a7ca4df1ad36dcd83c6a6eeb
Source dataset
uspto-grants-1977_07
Patent number
US04034098

Reaction notes

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