Methyl formate → HCID 20433017, compound

HRID 258728Notes

Reaction equation

HRID 258728 reaction equation
[CH2:1]([N:19]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH2:20][CH2:21][CH2:22][NH2:23])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH:42](OC)=[O:43]>C(O)C>[CH2:24]([N:19]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:20][CH2:21][CH2:22][NH:23][CH:42]=[O:43])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41]

Participants

4

Reactant 2

HCID 7865Methyl formateHCID 13956023N~1~,N~1~-Dioctadecylpropane-1,3-diamine

Product 1

HCID 20433017HCID 20433017, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of N,N-dioctadecyl-1,3-propanediamine (4.88 g.), ethanol (15 ml.) and methyl formate (35 ml.) is heated at reflux for one-half four. By-product methanol is distilled off and additional methyl formate (20 ml.) added. The mixture is refluxed for a half hour and allowed to stand overnight. It is taken to dryness under reduced pressure and the white solid residue recrystallized from ethyl acetate, Yield= quantitative: m.p. 42°-46° C.

Workup

  1. temperatureis heated
  2. temperatureat reflux for one-half four
  3. distillationBy-product methanol is distilled off
  4. additionadditional methyl formate (20 ml.) added
  5. temperatureThe mixture is refluxed for a half hour
  6. customthe white solid residue recrystallized from ethyl acetate
  7. customYield= quantitative

Sources & evidence

ORD record
ord-2a57fa7c513d4e6db047871052bb291c
Source dataset
uspto-grants-1977_07
Patent number
US04034040

Reaction notes

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