HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 2-[3-Bis(2-hydroxyethyl)aminopropyl]amino-quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-Chloroquinoline | HCID 11928 | — |
| Reactant | (3-Aminopropyl)diethanolamine | HCID 21088 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-[3-Bis(2-hydroxyethyl)aminopropyl]amino-quinoline | HCID 21424676 | — |
Reaction Steps
A mixture of 5.05 g. of 2-chloroquinoline, 5.5 g. of bis(2-hydroxyethyl)aminopropylamine and 3.0 g. of sodium carbonate is heated in 20 ml. of refluxing isopropanol for 24 hours. The reaction mixture is then filtered, solvent removed in vacuo and the residue chromatographed over silica gel to obtain an oil of 2-[3-bis(2-hydroxyethyl)aminopropyl]amino-quinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04035367 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-03178fbcc19d4bcd8274cb500c301743 |
| Source note | uspto-grants-1977_07 |