Sodium Hydroxide → HCID 53655731, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 38.5 parts of 1,3-dihydro-1-(1-methyl-2-phenylethenyl)-2H-benzimidazol-2-one, 5 parts of N,N,N-triethylbenzenemethanaminium chloride and 225 parts of sodium hydroxide solution 60% is stirred and heated at 55° C. Then there are added dropwise 30.9 parts of 1-bromo-4-chlorobutane. Upon completion, stirring at 55° C is continued for 4 hours. The reaction mixture is cooled, water is added and the oily product is extracted with methylbenzene. The extract is dried, filtered and evaporated, yielding 53 parts of 1-(4-chlorobutyl)-1,3-dihydro-3-(1-methyl-2-phenylethenyl)-2H-benzimidazol-2-one as a residue.

Provenance & Evidence