m-Chloroperbenzoic acid → HCID 53880775, compound

Participants

Reaction Steps

A solution of 2 g. of N,N-dimethyl-3-(8-chloro-dibenzo [b,f]thiepin-10-yl)-2-propynylamine in 100 ml. chloroform is treated at -50° C. with 1.2 g. of m-chloroperbenzoic acid. The solution is stirred for 15 minutes at this temperature, warmed to room temperature and chromatographed on basic aluminum oxide using chloroform/methanol (9:1) as the eluant, whereby there is obtained N,N-dimethyl-3-(8-chloro-dibenzo [b,f]thiepin-10-yl)-2-propynylamine N-oxide, which melts at 68°-69° C. after recrystallization from ethyl acetate/petroleum ether.

Provenance & Evidence