HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Dimethylmalonyl Dichloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sulfur Dioxide | HCID 1119 | — |
| Reactant | Dimethylmalonic acid | HCID 11686 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Dimethylmalonyl Dichloride | HCID 4523180 | — |
Reaction Steps
To a 500 ml. one-necked flask equipped with reflux condenser with drying tube, is added 50 grams (0.38 mole) dimethylmalonic acid (Aldrich Chemical Co.) and 300 ml. thionyl chloride. The mixture is heated to reflux for about 1 hour during which time the dimethylmalonic acid is dissolved and hydrogen chloride and sulfur dioxide are evolved. The unreacted thionyl chloride is removed by distillation under reduced pressure. The residue is recrystallized twice from cyclohexane to yield a white solid, M.P. 186°-187° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04035437 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-38581de9b1114be4935b945dafac826a |
| Source note | uspto-grants-1977_07 |