Hexanoic acid, 6-chloro-, ethyl ester → 5-[4-(1-Adamantyl)-phenoxy]-pentanecarboxylic acid ethyl ester

HRID 258980Notes

Reaction equation

HRID 258980 reaction equation
[CH2:1]([O:3][C:4]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]Cl)=[O:5])[CH3:2].[C:12]12([C:22]3[CH:27]=[CH:26][C:25]([OH:28])=[CH:24][CH:23]=3)[CH2:21][CH:16]3[CH2:17][CH:18]([CH2:20][CH:14]([CH2:15]3)[CH2:13]1)[CH2:19]2>>[CH2:1]([O:3][C:4]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:28][C:25]1[CH:24]=[CH:23][C:22]([C:12]23[CH2:13][CH:14]4[CH2:20][CH:18]([CH2:17][CH:16]([CH2:15]4)[CH2:21]2)[CH2:19]3)=[CH:27][CH:26]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 24999Hexanoic acid, 6-chloro-, ethyl esterHCID 2699334-(1-Adamantyl)phenol

Product 1

HCID 540544165-[4-(1-Adamantyl)-phenoxy]-pentanecarboxylic acid ethyl ester

Procedure

Analogously to the procedure describe in Example 5, the use of 5-chloro-pentanecarboxylic acid ethyl ester and p-(1-adamantyl)-phenol as starting materials gives 5-[4-(1-adamantyl)-phenoxy]-pentanecarboxylic acid ethyl ester of boiling point 170°-180° C (0.05 mm).

Sources & evidence

ORD record
ord-f4fd397fb0e34238ada31fbb5675a1e9
Source dataset
uspto-grants-1977_07
Patent number
US04035413

Reaction notes

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