HCID 21422772, compound → HCID 70633560, compound

HRID 259057Notes

Reaction equation

HRID 259057 reaction equation
[CH2:1]([NH:5][C:6]([O:8][C:9]1[CH:10]=[C:11]([CH:22]=[CH:23][CH:24]=1)[NH:12][C:13](=[O:21])[CH2:14][C:15](OC)([O:17][CH3:18])[CH3:16])=[O:7])[CH2:2][CH2:3][CH3:4]>C1(C)C=CC=CC=1>[CH2:1]([NH:5][C:6]([O:8][C:9]1[CH:10]=[C:11]([CH:22]=[CH:23][CH:24]=1)[NH:12][C:13](=[O:21])/[CH:14]=[C:15](\[O:17][CH3:18])/[CH3:16])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 21422772HCID 21422772, compound

Product 1

HCID 70633560HCID 70633560, compoundYield 84.8%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
140 °C

Procedure

A mixture of 43 g of m-(n-butylcarbamoyloxy)-3,3-dimethoxy-butyranilide and 400 ml of toluene were stirred at 140°C. for 2 hours while removing the methanol formed and was then cooled and vacuum filtered to obtain 33 g of m-(n-butylcarbamoyloxy)-3-methoxy-crotonanilide (isomer E) melting at 166°C.

Workup

  1. customwhile removing the methanol
  2. customformed
  3. temperaturewas then cooled
  4. filtrationvacuum filtered

Sources & evidence

ORD record
ord-67c3142d62a841d5a525e93dd9ab91f1
Source dataset
uspto-grants-1977_07
Patent number
US04036633

Reaction notes

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