4-Aminothiophenol → 4-(1H-Tetrazol-1-yl)benzene-1-thiol

Participants

Reaction Conditions

Reaction Steps

Alternatively a mixture of p-aminothiophenol (9.0 g.), sodium azide (7.0 g.), triethyl orthoformate (30 ml.), and acetic acid (30 ml.) was stirred and heated at 85° C. for 30 minutes. The reaction mixture was evaporated at reduced pressure and diluted with water to give a crystalline product which was collected and recrystallized from chloroform:hexane.

Provenance & Evidence