Dimethylamine → HCID 21423228, compound

HRID 259149Notes

Reaction equation

HRID 259149 reaction equation
C=O.[CH3:3][NH:4][CH3:5].[N:6]1([C:11]2[CH:16]=[CH:15][C:14]([SH:17])=[CH:13][CH:12]=2)[CH:10]=[N:9][N:8]=[N:7]1.[C:18](=O)([O-])[O-].[Na+].[Na+]>ClCCl>[CH3:3][N:4]([CH2:18][S:17][C:14]1[CH:13]=[CH:12][C:11]([N:6]2[CH:10]=[N:9][N:8]=[N:7]2)=[CH:16][CH:15]=1)[CH3:5]

Participants

6

Reactant 4

HCID 674DimethylamineHCID 712FormaldehydeHCID 10340Sodium CarbonateHCID 214232364-(1H-Tetrazol-1-yl)benzene-1-thiol

Product 1

HCID 21423228HCID 21423228, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To 1.0 ml. (10 mmol) of formalin at 0°-5° C. was added dropwise, with stirring, 1.1 ml. (10 mmol) of dimethylamine. After 20 minutes stirring, 1.78 g. (10 mmol) of p-(1H-tetrazol-1-yl)benzenethiol was added all at once followed by solid sodium carbonate. The mixture was stoppered, stirred vigorously for 11/2 hours, and dichloromethane added. The dichloromethane layer was washed with water, dried, and evaporated to give white crystals, m.p. 56°-57.5° C.

Workup

  1. stirringAfter 20 minutes stirring
  2. additionadded
  3. washThe dichloromethane layer was washed with water
  4. customdried
  5. customevaporated
  6. customto give white crystals, m.p. 56°-57.5° C.

Sources & evidence

ORD record
ord-5b5cc5b9f75c4cf0bef29c4375b1ca2f
Source dataset
uspto-grants-1977_07
Patent number
US04036849

Reaction notes

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