Water → HCID 21423232, compound

HRID 259151Notes

Reaction equation

HRID 259151 reaction equation
[N-:1]=[N+]=[N-].[Na+].[CH3:5][S:6][C:7]1[CH:12]=[CH:11][C:10]([N:13]2[CH:17]=[N:16][N:15]=[N:14]2)=[CH:9][CH:8]=1.S(=O)(=O)(O)O.C(Cl)(Cl)Cl.[OH2:27]>>[CH3:5][S:6]([C:7]1[CH:12]=[CH:11][C:10]([N:13]2[CH:17]=[N:16][N:15]=[N:14]2)=[CH:9][CH:8]=1)(=[NH:1])=[O:27]

Participants

6

Reactant 5

HCID 962WaterHCID 1118Sulfuric AcidHCID 6212ChloroformHCID 33557Sodium AzideHCID 21423234HCID 21423234, compound

Product 1

HCID 21423232HCID 21423232, compound

Procedure

Sodium azide (2.6 g.) was added at 35°-45° C. over 11/2 hours to a stirred mixture of 1.78 g. (0.01 mol) of 1-[p-(methylthio)phenyl]-1H-tetrazole and 6 ml. of concentrated sulfuric acid. After 4 additional hours of stirring the chloroform was poured off, the remaining paste diluted with water, filtered, and the filtrate adjusted to pH 8.5 and chilled. White crystals, m.p. 180°-181° C. were isolated.

Workup

  1. additionto a stirred mixture of 1.78 g
  2. additionwas poured off
  3. filtrationfiltered
  4. temperaturechilled
  5. customWhite crystals, m.p. 180°-181° C. were isolated

Sources & evidence

ORD record
ord-286fd0fbe6e04110b5a65a3f626cd87a
Source dataset
uspto-grants-1977_07
Patent number
US04036849

Reaction notes

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