3,4-Dichloroaniline → 2,3-Dibromo-N-[(3,4-dichlorophenyl)carbamoyl]propanamide

Participants

Reaction Conditions

Reaction Steps

16 g of 3,4-dichloroaniline are dissolved in 200 ml of dry benzene and a solution of 26.0 g of 2,3-dibromopropionyl isocyanate in 50 ml of benzene is added dropwise with cooling at 5° C. The urea formed is immediately precipitated in crystalline form. After stirring for 3 hours at 20° C., the reaction mixture is diluted with the same volume of petroleum ether, filtered and dried. Yield: 39.0 g, m.p: 174° - 175° C.

Provenance & Evidence