HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 259165Generated: October 29, 2026
4-Nitroaniline → 2,3-Dibromo-N-[(4-nitrophenyl)carbamoyl]propanamide
https://huagongshe.com/reaction/259165
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | 2,3-Dibromopropanoyl isocyanate | HCID 20318538 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2,3-Dibromo-N-[(4-nitrophenyl)carbamoyl]propanamide | HCID 21423284 | — |
Reaction Steps
14.0 g of 4-nitroaniline are dissolved in 200 ml of anhydrous acetonitrile, and 26.0 g of 2,3-dibromopropionyl isocyanate are added dropwise with cooling at 5° to 10° C. After stirring for 3 hours at 20° C., the solid precipitated is filtered off and dried. Yield: 35.0 g m.p.: 205° - 206° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04036850 |
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| Source dataset | uspto-grants-1977_07 |
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| ORD ID | ord-748fbac827a44e89b2907f8c75a45eae |
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| Source note | uspto-grants-1977_07 |
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