HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 259167Generated: October 29, 2026
4-Chloroaniline → 2,3-Dibromo-N-[(4-chlorophenyl)carbamoyl]propanamide
https://huagongshe.com/reaction/259167
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | 2,3-Dibromopropanoyl isocyanate | HCID 20318538 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2,3-Dibromo-N-[(4-chlorophenyl)carbamoyl]propanamide | HCID 21423317 | — |
Reaction Steps
A solution of 54 g of 2,3-dibromopropionyl isocyanate in 100 ml of benzene is added dropwise with cooling at 20° C. to a solution of 25 g of 4-chloroaniline in 250 ml of dry benzene. After stirring for 3 hours at 20° C., the suspension is diluted with 200 ml of petroleum ether, filtered and dried. Yield: 71.0 g, m.p.: 162° - 163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04036850 |
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| Source dataset | uspto-grants-1977_07 |
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| ORD ID | ord-0bf7e1cf6e304ad3b1ee57180cedaae7 |
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| Source note | uspto-grants-1977_07 |
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