Benzaldehyde → HCID 21423539, compound

Participants

Reaction Steps

A mixture of equimolar quantities of triphenyl phosphite, benzaldehyde, and sulfamide in chlorobenzene is warmed at 95°-100° C. for 2.5 hrs, and then the reaction mixture is stripped to 120°/0.2mm. The residue is recrystallized from acetonitrile and then from chlorobenzene, giving a white solid: mp 171°-174°; 31P nmr(DMSO-d6) -14.4(d, J = 25Hz); 1H nmr δ8.2(d of d, 1, J = 2 and 10Hz, NH), 6.9-7.6(m, 15, aryl), 6.7 (s, 2, NH2), 5.2(d of d, 1, J = 10 and 26, CH).

Provenance & Evidence