Chlorine → HCID 178430145, compound

HRID 259241Notes

Reaction equation

HRID 259241 reaction equation
[Cl:1]Cl.[NH2:3][C:4]1[N:13]=[C:12]([OH:14])[C:11]2[N:10]=[C:9]([CH3:15])[C:8]([CH3:17])([CH3:16])[NH:7][C:6]=2[N:5]=1.NC1N=C(O)C2N=C(CC)C(CCC)(CCC)NC=2N=1>C(O)(=O)C>[NH2:3][C:4]1[N:13]=[C:12]([OH:14])[C:11]2[N:10]=[C:9]([CH2:15][Cl:1])[C:8]([CH3:17])([CH3:16])[NH:7][C:6]=2[N:5]=1

Participants

5

Reactant 3

HCID 24526ChlorineHCID 178432362HCID 178432362, compoundHCID 178439210HCID 178439210, compound

Product 1

HCID 178430145HCID 178430145, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A slight excess of chlorine was added with stirring to 2-amino-4-hydroxy-6-methyl-7,7-dimethyl-7,8-dihydropteridine, (II, X = Me, R1 =R2 =n-Pr) in glacial acetic acid, and the resulting precipitate was filtered off and washed with dry ether, and isolated analogously to the procedure described in Example 3.

Workup

  1. filtrationthe resulting precipitate was filtered off
  2. washwashed with dry ether
  3. customisolated analogously to the procedure

Sources & evidence

ORD record
ord-5a789a8771514777872e237012289669
Source dataset
uspto-grants-1977_07
Patent number
US04036961

Reaction notes

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