HCID 178418361, compound → HCID 178422005, compound

Participants

Reaction Steps

To a solution of 1.2 g of NG -nitro-N2 -(6,7-dimethyl-1-naphthalenesulfonyl)-L-arginyl-N-tetrahydrofurfurylglycine benzyl ester in 20 ml of tert-butanol and 5 ml of acetic acid, was added 0.2 g of palladium black and then the mixture was shaken in a hydrogen atmosphere for 20 hours at room temperature. The solution was filtered to remove the catalyst and evaporated to give an oily product. Reprecipitation with ethanol-diethyl ether gave 0.8 g of N2 -(6,7-dimethyl-1-naphthalenesulfonyl)-L-arginyl-N-tetrahydrofurfurylglycine.

Provenance & Evidence