HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Oxo-1H-isothiochromene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-[(4-Oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzoic acid | HCID 2826383 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Oxo-1H-isothiochromene-3-carboxylic acid | HCID 345560 | — |
Reaction Steps
A mixture of 5- (o-carboxybenzylidene) rhodanine (4.68g.) and sodium hydroxide (5.0g.) in water (40ml.) was heated under reflux for 30 minutes, cooled and poured into 5N hydrochloric acid (250ml.). Filtration and recrystallisation from ethanol-water gave the product as a white solid, mp. 260.5° - 261° (lit mp. 261°-3°), (Found: C, 58.10; H, 2.92; S, 15.41. C10H6SO3 requires C, 58.24; H, 2.93; S, 15.55).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04036964 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-b9961e6d747c406e892ec897ca94cfdc |
| Source note | uspto-grants-1977_07 |