huagongshe.com
HRID25928

反应详情

EQUATION

反应方程式

HRID 25928 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(C=O)no1
HCID2795222

5-methylisoxazole-3-carbaldehyde

C5H5NO2

结构：Cl.NN1CCNC1=O
HCID19261678

1-Aminoimidazolidin-2-one--hydrogen chloride (1/1)

C3H8ClN3O

PRODUCTS

生成物

1
结构：Cc1cc(C=NN2CCNC2=O)no1
HCID54221130

1-{[(5-Methyl-1,2-oxazol-3-yl)methylidene]amino}imidazolidin-2-one

C8H10N4O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

14.0 pts. by wt. of 5-methyl-3-formyl-isoxazole are reacted with 25.6 pts. by wt. of 1-amino-2-oxo-imidazolidine hydrochloride in 100 pts. by vol. of water as in Example 25.1. After 90 minutes, the precipitate is filtered off, washed with water, dried and recrystallised from absolute acetonitrile. 12.5 pts. by wt. of 1-(5-methyl-isoxazol-3-yl-methyleneamino)-2-oxo-imidazolidine of melting point 195°-7° C. are obtained.

WORKUP

后处理

  1. filtrationthe precipitate is filtered off
  2. washwashed with water
  3. customdried
  4. customrecrystallised from absolute acetonitrile